A fast and accurate algorithm for single individual haplotyping

Probabilistic single-individual haplotyping

MOTIVATION Accurate haplotyping-determining from which parent particular portions of the genome are inherited-is still mostly an unresolved problem in genomics. This problem has only recently started to become tractable, thanks to the development of new long read sequencing technologies. Here, we introduce ProbHap, a haplotyping algorithm targeted at such technologies. The main algorithmic idea...

a new algorithm and software of individual life insurance and annuity computation

چکیده ندارد.

A Fast and Accurate Heuristic for the Single Individual SNP Haplotyping Problem with Many Gaps, High Reading Error Rate and Low Coverage

Fosmid-based whole genome haplotyping of a HapMap trio child: evaluation of Single Individual Haplotyping techniques

Determining the underlying haplotypes of individual human genomes is an essential, but currently difficult, step toward a complete understanding of genome function. Fosmid pool-based next-generation sequencing allows genome-wide generation of 40-kb haploid DNA segments, which can be phased into contiguous molecular haplotypes computationally by Single Individual Haplotyping (SIH). Many SIH algo...

A fast and accurate single frequency estimator

A new frequency estimator for a single complex sinusoid in complex white Gaussian noise is proposed. The estimator is more computationally efficient than the optimal maximum likelihood estimator yet attains as good performance at moderately high signal-tonoise ratios. Also, the estimator is shown to be related to the linear prediction estimator. This relationship is exploited to reveal why the ...